化工进展 ›› 2012, Vol. 31 ›› Issue (02 ): 345-354.

• 材料科学与技术 • 上一篇    下一篇

磁性壳聚糖微球的研究进展

宋艳艳1,2,孔维宝1,宋  昊1,华绍烽1,夏春谷1   

  1. 1中国科学院兰州化学物理研究所,羰基合成与选择氧化国家重点实验室,甘肃 兰州 730000;
    2中国科学院研究生院,北京 100049)
  • 出版日期:2012-02-05 发布日期:2012-02-05

Reseach progress in magnetic chitosan microspheres

SONG Yanyan1,2,KONG Weibao1,SONG Hao1,HUA Shaofeng1,XIA Chungu1   

  1. (1State Key Laboratory for Oxo Synthesis and Selective Oxidation,Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences,Lanzhou 730000,Gansu,China;2Graduate University of Chinese Academy of Sciences,Beijing 100049,China)
  • Online:2012-02-05 Published:2012-02-05

摘要: 磁性氧化铁纳米粒子(Fe3O4,γ-Fe2O3等)因具有尺寸小、超顺磁性和低毒性等特点,已经引起了生物化工、医药工业研究领域的广泛关注。磁性壳聚糖微球具有表面非常光滑的球形结构。近年来,已经制备出了平均粒径在 10~2.5×105 nm 之间的磁性壳聚糖微球,并在生物医药、食品工程和污水处理等许多领域已经取得了初步的应用,特别是在污水处理和酶固定化领域。本文综述了近年来磁性氧化铁纳米粒子和磁性壳聚糖微球的制备方法、磁性壳聚糖微球的改性方法及应用的最新研究成果。

关键词: 磁性壳聚糖微球, 固定化, 四氧化三铁, 纳米材料, magnetic chitosan microspheres, immobilization, Fe3O4, nano-material, 磁性壳聚糖微球, 固定化, 四氧化三铁, 纳米材料

Abstract: Magnetic iron oxide(Fe3O4,γ-Fe2O3 etc.) nanoparticles have attracted researchers in various fields such as biochemical engineering and medicine industrical due to their small size,superparamagnetism and low toxicity. Magnetic chitosan microspheres are in sphere shape with a rather smooth surface. In recent years,magnetic chitosan microspheres were prepared with a mean size range of 10 nm to 2.5×105 nm. Magnetic chitosan microspheres have been preliminarily applied in various fields,including biomedicine,food engineering and wastewater treatment,etc,especially in the fields of wastewater treatment and enzyme immobilization. The preparation methods of magnetic iron oxide nanoparticles and magnetic chitosan microspheres,the recent achievements including modification methods and applications of magnetic chitosan microspheres,are reviewed in this paper.

Key words: magnetic chitosan microspheres, immobilization, Fe3O4, nano-material

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